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Sildenafil can be a strong and selective inhibitor of cGMP-unique phosphodiesterase kind 5 (PDE5), that's to blame for degradation of cGMP during the corpus cavernosum. The molecular composition of sildenafil is analogous to that of cGMP and functions being a competitive binding agent of PDE5 inside the corpus cavernosum, resulting in more cGMP and

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